N-(2-chlorophenyl)-2-[methyl(2-pyrrolidin-1-ylethyl)amino]propanamide,hydrochloride

名称

[ CAS 号 ]:
102129-03-3

[ 英文名 ]:
N-(2-chlorophenyl)-2-[methyl(2-pyrrolidin-1-ylethyl)amino]propanamide,hydrochloride

[英文别名 ]:

C 5407

物理化学性质

[ 沸点 ]:
459.5ºC at 760 mmHg

[ 分子式 ]:
C₁₆H₂₅Cl₂N₃O

[ 分子量 ]:
346.29500

[ 闪点 ]:
231.7ºC

[ 精确质量 ]:
345.13700

[ PSA ]:
39.07000

[ LogP ]:
4.08400

[ 蒸汽压 ]:
1.26E-08mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UE4782000

CHEMICAL NAME :: Propionanilide, o-chloro-2-(methyl(2-(pyrrolidinyl)ethyl)amino)-, dihydrochloride

CAS REGISTRY NUMBER :: 102129-03-3

LAST UPDATED :: 199012

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C16-H24-Cl-N3-O.2Cl-H

MOLECULAR WEIGHT :: 382.80

WISWESSER LINE NOTATION :: T5NTJ A2N1&Y1&VMR BG &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,262,1959 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 112 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,262,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 855 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,262,1959