草酸苄唑啉盐

草酸苄唑啉盐用途

I2咪唑啉受体激动剂；对I2咪唑啉受体具有比α-肾上腺素受体高的亲和力和选择性。 I2 imidazoline receptor agonist; has high affinity and selectivity for I2 imidazoline receptors over α-adrenoceptors.

草酸苄唑啉盐名称

[ CAS 号 ]:
1021868-82-5

[ 中文名 ]:
草酸苄唑啉盐

[ 英文名 ]:
Benazoline oxalate salt

[英文别名 ]:

2-(2-Naphthyl)-1H-imidazole ethanedioate (1:1)
Benazoline oxalate salt

草酸苄唑啉盐物理化学性质

[ 分子式 ]:
C₁₃H₁₂N₂•(C₂H₂O₄)

[ 分子量 ]:
196.259003

[ 精确质量 ]:
284.079712

[ 水溶解性 ]:
Soluble in water: ≤8 mg/mL'}

草酸苄唑啉盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危险品运输编码 ]:
NONH for all modes of transport

草酸苄唑啉盐文献

Coupling of I(1) imidazoline receptors to the cAMP pathway: studies with a highly selective ligand, benazoline.

Mol. Pharmacol. 57 , 1142-51, (2000)

Clonidine and benazoline are two structurally related imidazolines. Whereas clonidine binds both to alpha(2)-adrenoceptors (alpha(2)R) and to I(1) imidazoline receptors (I(1)R), benazoline showed a hi...

Imidazoline receptors: qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity.

Bioorg. Med. Chem. 5(5) , 833-841, (1997)

The observation that all the attempts to characterize imidazoline (I) receptors have been carried out with non-selective or poorly selective ligands prompted us to undertaken research aimed at develop...

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