2,2-D2,2-二甲基-3-(2-甲基丙-1-烯-1-基)环丙烷甲酸

用途

菊花酸(NSC 11779)是一种有机化合物,与多种天然和合成杀虫剂有关,用于预防虫媒疾病等[1]。

名称

[ CAS 号 ]:
10453-89-1

[ 中文名 ]:
菊甲酸

[ 英文名 ]:
Cyclopropanecarboxylicacid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-

[中文别名 ]:

[英文别名 ]:

生物活性

[ 描述 ]:

菊花酸(NSC 11779)是一种有机化合物,与多种天然和合成杀虫剂有关,用于预防虫媒疾病等[1]。

[ 相关类别 ]:

研究领域 >> 其他
信号通路 >> 其他 >> 其他

[参考文献]

[1]. Takanori Yamashiro, et al. Draft genome of Tanacetum cinerariifolium, the natural source of mosquito coil. Sci Rep. 2019 Dec 3;9(1):18249.  

物理化学性质

[ 密度 ]:
1.077g/cm3

[ 沸点 ]:
246.4ºC at 760 mmHg

[ 熔点 ]:
50-51 °C

[ 分子式 ]:
C10H16O2

[ 分子量 ]:
168.23300

[ 闪点 ]:
119ºC

[ 精确质量 ]:
168.11500

[ PSA ]:
37.30000

[ LogP ]:
2.30940

[ 外观性状 ]:
固体

[ 蒸汽压 ]:
0.0088mmHg at 25°C

[ 折射率 ]:
1.546

[ 储存条件 ]:
室温， 密封， 干燥

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GZ1270000
CHEMICAL NAME :
Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-
CAS REGISTRY NUMBER :
10453-89-1
BEILSTEIN REFERENCE NO. :
2043418
LAST UPDATED :
199701
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C10-H16-O2
MOLECULAR WEIGHT :
168.26
WISWESSER LINE NOTATION :
L3TJ A1 A1 BVQ C1UY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>400 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>400 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
>586 mg/m3
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
1248 mg/m3
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),16,1986

安全信息

[ 危害码 (欧洲) ]:
Xn

[ 海关编码 ]:
2916209090

合成路线

详细合成路线

上下游产品

上游产品

下游产品

海关

[ 海关编码 ]: 2916209090

[ 中文概述 ]:
2916209090 其他（环烷、环烯、环萜烯）一元羧酸（包括酸酐、酰卤化物，过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙烯酸、丙烯酸盐或酯应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
2916209090 other cyclanic, cyclenic or cyclotherpenic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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热门化合物

CAS号[10453-89-1]化源网提供[2,2-D2,2-二甲基-3-(2-甲基丙-1-烯-1-基)环丙烷甲酸]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版：2,2-D2,2-二甲基-3-(2-甲基丙-1-烯-1-基)环丙烷甲酸

标题：10453-89-1_CAS号:10453-89-1_2,2-D2,2-二甲基-3-(2-甲基丙-1-烯-1-基)环丙烷甲酸 - 化源网 地址：https://www.chemsrc.com/amp/cas/10453-89-1_448887.html