GHRP-6 acetate

GHRP-6 acetate is a synthetic growth hormone (GH) secretagogue and an agonist of the GH secretagogue receptor (GHS-R), which is also known as the ghrelin receptor. It inhibits binding of the GHS-R agonist MK-0677 (Ibutamoren) to COS-7 cell membranes expressing human GHS-R type Ia and binding of ghrelin to COS-7 cells expressing human GHS-R. GHRP-6 stimulates intracellular calcium mobilization in BHK cells expressing the human receptor and inositol phosphate production in COS-7 cells expressing the human receptor. It also acts as a negative allosteric modulator of ghrelin signaling. GHRP-6 induces release of GH, but not thyroid-stimulating hormone (TSH), luteinizing hormone (LH), or follicle-stimulating hormone (FSH), in isolated rat pituitary gland. It increases levels of GH, but not TSH, LH, FSH, or prolactin, in rat blood when administered subcutaneously at a dose of 50 μg. GHRP-6 increases food intake in rats when administered intracerebroventricularly at 0.3, 1, and 3 nmol.

[ 分子式 ]:
C₅₂H₆₈N₁₂O₁₂

[ 分子量 ]:
1053.17000

[ 精确质量 ]:
1052.51000

[ PSA ]:
431.23000

[ LogP ]:
8.05290

公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐乾明

产品详情：GHRP-6 (acetate)

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公司名：上海脉铂医药科技有限公司

区域：上海市嘉定区

价格：
￥1065.0/5mg ￥6370.0/50mg ￥1820.0/10mg ￥需询单/10mg

联系人：李先生

产品详情：GHRP-6 (acetate)

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