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毛花洋地黄苷B

毛花洋地黄苷B用途

Lanatoside B是一种可以从洋地黄叶片中分离出来的卡酚内酯[1]。

毛花洋地黄苷B名称

[ CAS 号 ]:
17575-21-2

[ 中文名 ]:
毛花洋地黄苷B

[ 英文名 ]:
Lanatoside B

[中文别名 ]:

毛花洋地黄苷 b

[英文别名 ]:

Lanatosid-B
LANTOSIDEB
digilanidb
Digilanide B

毛花洋地黄苷B生物活性

[ 描述 ]:

Lanatoside B是一种可以从洋地黄叶片中分离出来的卡酚内酯[1]。

[ 相关类别 ]:

研究领域 >> 心血管疾病

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Fernão Castro Braga, et al. Variation of cardenolides with growth in a Digitalis lanata Brazilian cultivar. Phytochemistry, 45 (3), 1997, 473-476.

毛花洋地黄苷B物理化学性质

[ 密度 ]:
1.42g/cm3

[ 熔点 ]:
245-248ºC

[ 分子式 ]:
C₄₉H₇₆O₂₀

[ 分子量 ]:
985.12

[ 精确质量 ]:
984.49300

[ PSA ]:
288.28000

[ LogP ]:
0.61310

[ 折射率 ]:
1.608

毛花洋地黄苷B毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OE2040000

CHEMICAL NAME :: Lanatoside B

CAS REGISTRY NUMBER :: 17575-21-2

BEILSTEIN REFERENCE NO. :: 0078394

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C49-H76-O20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 177,60,1934

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 388 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 31,236,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 3695 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 252,314,1966 *** REVIEWS *** TOXICOLOGY REVIEW 85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year: -,52,1963