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(3-丙羧基)三苯基溴化膦

(3-丙羧基)三苯基溴化膦名称

[ CAS 号 ]:
17857-14-6

[ 中文名 ]:
(3-丙羧基)三苯基溴化膦

[ 英文名 ]:
(3-Carboxypropyl)(triphenyl)phosphonium bromide

[中文别名 ]:

[英文别名 ]:

(3-Carboxypropyl)triphenylphosphonium bromide
(3-Carboxypropyl)(triphenyl)phosphonium bromide
Ph3PCH2CH2CH2COOH bromide
(4-Hydroxy-4-oxobutyl)triphenylphosphonium bromide
MFCD00274196
3-Carboxypropyl triphenylphosphonium bromide

(3-丙羧基)三苯基溴化膦物理化学性质

[ 熔点 ]:
244-247 °C(lit.)

[ 分子式 ]:
C₂₂H₂₂BrO₂P

[ 分子量 ]:
429.287

[ 精确质量 ]:
428.054077

[ PSA ]:
50.89000

[ LogP ]:
0.84930

[ 外观性状 ]:
白色粉末和颗粒

[ 储存条件 ]:
室温

[ 水溶解性 ]:
可溶于：甲醇

(3-丙羧基)三苯基溴化膦MSDS

详细MSDS(安全技术说明书)

(3-丙羧基)三苯基溴化膦安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

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(3-丙羧基)三苯基溴化膦文献

Mitochondrial delivery of doxorubicin via triphenylphosphine modification for overcoming drug resistance in MDA-MB-435/DOX cells.

Mol. Pharm. 11(8) , 2640-9, (2014)

In this study, doxorubicin (DOX) was conjugated to a lipophilic triphenylphosphonium (TPP) that is selectively taken up by the mitochondrial membrane of cells. This new derivative of DOX, i.e., TPP-DO...

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