<生产厂家价格>

特戊酸氯甲酯

特戊酸氯甲酯用途

【用途一】
用于医药中间体，是第二代口服头孢类抗生素头孢他类酯和头孢特酯的原料
【用途二】
有机中间体。

特戊酸氯甲酯名称

[ CAS 号 ]:
18997-19-8

[ 中文名 ]:
特戊酸氯甲酯

[ 英文名 ]:
Chloromethyl pivalate

[中文别名 ]:

[英文别名 ]:

Methanol,chloro-,pivalate
chloromethyl trimethylacetate
Propanoic acid, 2,2-dimethyl-, chloromethyl ester
pivalic acid chloromethyl ester
POM-CL
Chloromethyl Pivalate [Amino-Protecting Agent]
Chloromethyl 2,2-dimethylpropanoate
CHLOROMETHYL PIVARATE
chloromethyl 2,2-dimethylpropionate
Pivaloxymethylchlorde

特戊酸氯甲酯物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
143.0±13.0 °C at 760 mmHg

[ 熔点 ]:
<-40ºC

[ 分子式 ]:
C₆H₁₁ClO₂

[ 分子量 ]:
150.603

[ 闪点 ]:
40.0±0.0 °C

[ 精确质量 ]:
150.044754

[ PSA ]:
26.30000

[ LogP ]:
1.64

[ 外观性状 ]:
无色透明液体，相对密度1.045，沸点146-148℃，折光率1.4170，闪点40℃。

[ 蒸汽压 ]:
5.5±0.3 mmHg at 25°C

[ 折射率 ]:
1.425

[ 储存条件 ]:
Flammables area

特戊酸氯甲酯MSDS

特戊酸氯甲酯安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H226-H302 + H312 + H332-H315-H319-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R10;R36/37/38

[ 安全声明 (欧洲) ]:
S16-S26-S36-S41-S36/37/39

[ 危险品运输编码 ]:
UN 3272 3/PG 3

[ WGK德国 ]:
3

[ 包装等级 ]:
III

[ 危险类别 ]:
3

[ 海关编码 ]:
2915600000

特戊酸氯甲酯合成路线

特戊酸氯甲酯上下游产品

特戊酸氯甲酯上游产品

特戊酸氯甲酯下游产品

特戊酸氯甲酯制备

由特戊酰氯经氯甲基化而得。

特戊酸氯甲酯海关

[ 海关编码 ]: 2915900090

[ 中文概述 ]:
2915900090. 其他饱和无环一元羧酸及其酸酐（酰卤、过氧）化物、过氧酸及其卤化、硝化、磺化、亚硝化衍生物. 增值税率:17.0%. 退税率:9.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

特戊酸氯甲酯文献

Synthesis of an Isoindoline-Annulated, Tricyclic Sultam Library via Microwave-Assisted, Continuous-Flow Organic Synthesis (MACOS).

Synthesis 44(16) , doi:10.1055/s-0031-1289791, (2012)

A microwave-assisted, continuous-flow organic synthesis (MACOS) protocol for the synthesis of an isoindoline-annulat-ed, tricyclic sultam library, utilizing a Heck-aza-Michael (HaM) strategy, is repor...

Synthesis and in vitro evaluation of a phosphonate prodrug: bis(pivaloyloxymethyl) 9-(2-phosphonylmethoxyethyl)adenine.

Antiviral Res. 19(3) , 267-73, (1992)

9-(2-Phosphonylmethoxyethyl)adenine (PMEA; 1) was acylated with chloromethyl pivalate to afford bis(pivaloyloxymethyl) PMEA (2). The ester prodrug demonstrated enhanced in vitro potency against HSV-2 ...

An efficient method for the synthesis of sulbactam pivoxil.

Il Farmaco 55(2) , 134-5, (2000)

Sulbactam pivoxil, a prodrug of the beta-lactamase inhibitor sulbactam, was prepared in high yield by reacting the sodium salt of sulbactam with chloromethyl pivalate in a polar solvent, then diluting...

更多文献