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油酸单乙醇胺

油酸单乙醇胺用途

油酸(9-顺十八烯酸)乙醇胺由油酸和乙醇胺组成。油酸乙醇胺具有硬化治疗活性。油酸乙醇胺可引起静脉内膜内皮的炎症反应[1]。

油酸单乙醇胺名称

[ CAS 号 ]:
2272-11-9

[ 中文名 ]:
油酸单乙醇胺

[ 英文名 ]:
monoethanolamine oleate

[英文别名 ]:

Neosclerol
Monolate
Ethamolin
Moramin
Monoethanolamine oleate
ETHANOLAMINE OLEATE
Oldamin
Varicetin
Varex

油酸单乙醇胺生物活性

[ 描述 ]:

油酸(9-顺十八烯酸)乙醇胺由油酸和乙醇胺组成。油酸乙醇胺具有硬化治疗活性。油酸乙醇胺可引起静脉内膜内皮的炎症反应[1]。

[ 相关类别 ]:

研究领域 >> 心血管疾病

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[ 靶点 ]

Inflammation[1]

[参考文献]

[1]. Kiripolsky MG. More on ethanolamine oleate as a vascular sclerosant. Dermatol Surg. 2010 Jul;36(7):1153-4.

油酸单乙醇胺物理化学性质

[ 密度 ]:
0.973g/cm3

[ 沸点 ]:
170.9ºC at 760mmHg

[ 分子式 ]:
C₂₀H₄₁NO₃

[ 分子量 ]:
343.54400

[ 闪点 ]:
93.3ºC

[ 精确质量 ]:
343.30900

[ PSA ]:
83.55000

[ LogP ]:
5.74620

[ 蒸汽压 ]:
3.7E-06mmHg at 25°C

油酸单乙醇胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RG2900000

CAS REGISTRY NUMBER :: 2272-11-9

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C18-H34-O2.C2-H7-N-O

MOLECULAR WEIGHT :: 343.62

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 156 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 17,357,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 175 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 17,373,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1228 No. of Facilities: 1996 (estimated) No. of Industries: 22 No. of Occupations: 31 No. of Employees: 40126 (estimated) No. of Female Employees: 2760 (estimated)

油酸单乙醇胺安全信息

[ 海关编码 ]:
2922499990

油酸单乙醇胺海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%