(Z)-but-2-enedioic acid,1-[10-[2-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one

名称

[ CAS 号 ]:
3568-23-8

[ 英文名 ]:
(Z)-but-2-enedioic acid,1-[10-[2-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one

[英文别名 ]:

Propiomazine hydrogen maleate
Dorevane
Propionylpromethazine maleate
Indorm
Propavan
Propiomazine maleate
EINECS 222-661-6

物理化学性质

[ 沸点 ]:
682.7ºC at 760 mmHg

[ 分子式 ]:
C₂₄H₂₈N₂O₅S

[ 分子量 ]:
456.55500

[ 闪点 ]:
366.7ºC

[ 精确质量 ]:
456.17200

[ PSA ]:
123.45000

[ LogP ]:
4.60890

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UC1935000

CHEMICAL NAME :: 1-Propanone, 1-(10-(2-dimethylaminopropyl)-phenothiazin-2-yl)-, maleate

CAS REGISTRY NUMBER :: 3568-23-8

LAST UPDATED :: 199706

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C20-H24-N2-O-S.C4-H4-O4

MOLECULAR WEIGHT :: 456.60

WISWESSER LINE NOTATION :: T C666 BN ISJ BY1&1N1&1 GV2 &QV1U1VQ -C

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 123,78,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 288 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 119,367,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 67 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 123,78,1959

安全信息

[ 海关编码 ]:
2934300000

海关

[ 海关编码 ]: 2934300000

[ 中文概述 ]:
2934300000. 含一个吩噻嗪环系的化合物(吩噻嗪环系不论是否氢化,化合物未经进一步稠合的 ). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%