(R)-AM1241
(R)-AM1241用途
(R)-AM1241 acts as an agonist at human CB2 receptors but an inverse agonist at rat and mouse CB2 receptors. Similar to the racemate AM1241, (R)-AM1241 produces antinociception to thermal pain but not mechanical pain in rats. The pain-reducing effect of (R)-AM1241 is blocked by the CB2-specific inhibitor SR 144528 but not by either the CB1-selective inhibitor rimonabant or the opioid receptor blocker naloxone.
(R)-AM1241名称
(R)-AM1241物理化学性质
[ 密度 ]:
1.6±0.1 g/cm3
[ 沸点 ]:
630.7±55.0 °C at 760 mmHg
[ 分子式 ]:
C22H22IN3O3
[ 分子量 ]:
503.333
[ 闪点 ]:
335.2±31.5 °C
[ 精确质量 ]:
503.070587
[ PSA ]:
71.06000
[ LogP ]:
4.85
[ 蒸汽压 ]:
0.0±1.8 mmHg at 25°C
[ 折射率 ]:
1.696
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相关化合物
[(R)-AM1241]化源网提供(R)-AM1241CAS号444912-51-0,(R)-AM1241MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询(R)-AM1241上化源网,专业又轻松。>>电脑版:(R)-AM1241
标题:444912-51-0_(R)-AM1241CAS号:444912-51-0_(R)-AM1241【结构式 性质 英文】 - 化源网 地址:https://www.chemsrc.com/amp/cas/444912-51-0_452571.html