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胡萝卜苷

胡萝卜苷用途

胡萝卜苷 (Daucosterol)是一种天然的甾醇体类化合物。

胡萝卜苷名称

[ CAS 号 ]:
474-58-8

[ 中文名 ]:
西托糖苷

[ 英文名 ]:
Daucosterol

[中文别名 ]:

[英文别名 ]:

β-D-Glucopyranoside, (3β)-stigmast-5-en-3-yl
Daucosterin
lyoniside
Coriandrinol
(3b)-Stigmast-5-en-3-yl b-D-Glucopyranoside
Sitogluside
β-Sitosterol β-D-glucoside
β-sitosterol-D-glucoside
b-Daucosterol
b-Sitosteryl glucoside

胡萝卜苷生物活性

[ 描述 ]:

胡萝卜苷 (Daucosterol)是一种天然的甾醇体类化合物。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

天然产物 >> 类固醇

研究领域 >> 癌症

[参考文献]

[1]. Jiang LH, et al. Daucosterol protects neurons against oxygen-glucose deprivation/reperfusion-mediated injury by activating IGF1 signaling pathway. J Steroid Biochem Mol Biol. 2015 Aug;152:45-52.

[2]. Jiang LH, et al. Daucosterol promotes the proliferation of neural stem cells. J Steroid Biochem Mol Biol. 2014 Mar;140:90-9.

[3]. Zhao C, et al. Daucosterol inhibits cancer cell proliferation by inducing autophagy through reactive oxygen species-dependent manner. Life Sci. 2015 Sep 15;137:37-43.

[相关活性小分子]

胡萝卜苷物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
673.6±55.0 °C at 760 mmHg

[ 分子式 ]:
C₃₅H₆₀O₆

[ 分子量 ]:
576.847

[ 闪点 ]:
361.2±31.5 °C

[ 精确质量 ]:
576.438965

[ PSA ]:
99.38000

[ LogP ]:
8.78

[ 外观性状 ]:
灰白色粉末

[ 蒸汽压 ]:
0.0±4.7 mmHg at 25°C

[ 折射率 ]:
1.554

[ 储存条件 ]:
2-8°C

胡萝卜苷MSDS

详细MSDS(安全技术说明书)

胡萝卜苷毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WJ2508000

CHEMICAL NAME :: Stigmast-5-ene, 3-beta-(beta-D-glucopyranosyloxy)-

CAS REGISTRY NUMBER :: 474-58-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C35-H60-O6

MOLECULAR WEIGHT :: 576.95

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 62 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJPAAO Indian Journal of Pharmacy. (Bombay, India) V.1-40(1), 1939-78. For publisher information, see IJSIDW. Volume(issue)/page/year: 29,91,1967

胡萝卜苷安全信息

[ 安全声明 (欧洲) ]:
24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
29389090

胡萝卜苷合成路线

详细合成路线

胡萝卜苷上下游产品

胡萝卜苷上游产品

胡萝卜苷下游产品

胡萝卜苷文献

[Chemical constituents contained in seeds of Notopterygium franchetii].

Zhongguo Zhong Yao Za Zhi 37(7) , 941-5, (2012)

To study the chemical constituents from the seeds of Notopterygium franchetii.Ethanol extracts of seeds N. franchetii were separated and purified by such methods as normal and reversed phase column ch...

[Study on the chemical constituets in ethyl acetante extraction from semen litchi].

Zhong Yao Cai 35(1) , 64-6, (2012)

To study the chemical constituents in ethyl acetate extraction of Semen Litchi.The compounds were isolated and purified by column chromatography on silica gel and Sephadex LH-20 coupled with preparati...

[Chemical constituents from stems of Dysoxylum laxiracemosum].

Zhongguo Zhong Yao Za Zhi 37(9) , 1237-40, (2012)

Twelve compounds were separated from stems of Dysoxylum laxiracemosum and their structures were identified by spectrum analysis as shoreic acid (1), cabraleahydroxylactone (2), cabralealactone (3), ci...

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