DL-甲基多巴
DL-甲基多巴名称
[ CAS 号 ]:
555-29-3
[ 中文名 ]:
DL-甲基多巴
[ 英文名 ]:
3-Hydroxy-alpha-methyl-DL-tyrosine
[中文别名 ]:
[英文别名 ]:
- a-Methyl-L-dopa
- α-Methyl-L-dopa
- Dopegyt
- EINECS 209-088-7
- 3-(3,4-Dihydroxyphenyl)-2-methyl alanine
- L-(-)-b-(3,4-Dihydroxyphenyl)-a-methylalanine
- L-(-)-α-Methyl-β-(3,4-dihydroxyphenyl)alanine
- L-(-)-a-Methyl-b-(3,4-dihydroxyphenyl)alanine
- rac Alpha-Methyl DOPA
- 2-Methyl-3-(3,4-dihydroxyphenyl)-DL-alanine
DL-甲基多巴物理化学性质
[ 密度 ]:
1.4±0.1 g/cm3
[ 沸点 ]:
441.6±45.0 °C at 760 mmHg
[ 分子式 ]:
C10H13NO4
[ 分子量 ]:
211.214
[ 闪点 ]:
220.9±28.7 °C
[ 精确质量 ]:
211.084457
[ PSA ]:
103.78000
[ LogP ]:
0.13
[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C
[ 折射率 ]:
1.635
[ 储存条件 ]:
−20°C
DL-甲基多巴毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AY5940000
- CHEMICAL NAME :
- Alanine, 3-(3,4-dihydroxyphenyl)-2-methyl-, DL-
- CAS REGISTRY NUMBER :
- 555-29-3
- LAST UPDATED :
- 199403
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C10-H13-N-O4
- MOLECULAR WEIGHT :
- 211.24
- WISWESSER LINE NOTATION :
- QVXZ1&1R CQ DQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5710 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 430 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5370 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1317 mg/kg
- TOXIC EFFECTS :
- Liver - hepatitis (hepatocellular necrosis), diffuse Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1318,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1760 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989
DL-甲基多巴安全信息
[ 危害码 (欧洲) ]:
Xi
[ 风险声明 (欧洲) ]:
36
[ 安全声明 (欧洲) ]:
26-36/37
[ WGK德国 ]:
3
推荐生产厂家/供应商：
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥6296.0/5g
￥需询单/1g
￥需询单/1g
￥需询单/1g
联系人：阿拉丁
公司名：武汉鼎信通药业有限公司
区域：武汉市江夏区
价格：
￥需询单/1kg
$需询单/10kg
$需询单/50kg
$需询单/500kg
联系人：董浩
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相关化合物
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