黄尿酸
黄尿酸用途
黄尿酸名称
[ CAS 号 ]:
59-00-7
[ 中文名 ]:
4,8-二羟基喹啉-2-甲酸
[ 英文名 ]:
Xanthurenic acid
[中文别名 ]:
[英文别名 ]:
- 4,8-Dihydroxy-2-quinolinecarboxylic acid
- EINECS 200-410-1
- 4,8-dihydroxy-Quinaldic acid
- 4,8-Dihydroxyquinoline-2-carboxylic acid
- 8-hydroxy-4-oxo-1H-quinoline-2-carboxylic acid
- Xanthurenate
- Xanthurenic acid
- MFCD00006754
- 2-Quinolinecarboxylic acid, 4,8-dihydroxy-
黄尿酸生物活性
[ 描述 ]:
[ 相关类别 ]:
[ 靶点 ]
Human Endogenous Metabolite
mGluR2
mGluR3
[体内研究]
[动物实验]
[参考文献]
[相关活性小分子]
黄尿酸物理化学性质
[ 密度 ]:
1.6±0.1 g/cm3
[ 沸点 ]:
514.4±50.0 °C at 760 mmHg
[ 熔点 ]:
297-298 °C (dec.)(lit.)
[ 分子式 ]:
C10H7NO4
[ 分子量 ]:
205.167
[ 闪点 ]:
264.9±30.1 °C
[ 精确质量 ]:
205.037506
[ PSA ]:
90.65000
[ LogP ]:
2.64
[ 外观性状 ]:
固体;Light yellow to Amber to Dark green powder to crystal
[ 蒸汽压 ]:
0.0±1.4 mmHg at 25°C
[ 折射率 ]:
1.779
[ 储存条件 ]:
Store at RT
黄尿酸MSDS
黄尿酸毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UZ9275000
- CHEMICAL NAME :
- Quinaldic acid, 4,8-dihydroxy-
- CAS REGISTRY NUMBER :
- 59-00-7
- BEILSTEIN REFERENCE NO. :
- 0185954
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C10-H7-N-O4
- MOLECULAR WEIGHT :
- 205.18
- WISWESSER LINE NOTATION :
- T66 BNJ CVQ EQ JQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 160 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - tumors
- REFERENCE :
- ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 108,924,1963 *** REVIEWS *** TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971
黄尿酸安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H315-H319-H335
[ 警示性声明 ]:
P261-P305 + P351 + P338
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves
[ 危害码 (欧洲) ]:
Xi: Irritant;
[ 风险声明 (欧洲) ]:
R36/37/38
[ 安全声明 (欧洲) ]:
S26-S36
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
3
[ RTECS号 ]:
UZ9275000
黄尿酸制备
用由芬顿试剂(Fenton reagent)得到的羟基游离基与犬尿喹啉酸作用制取。
黄尿酸文献
J. Chromatogr. A. 562(1-2) , 125-38, (1991)
Eighty-five clinical urine samples and nineteen urine samples previously found by other laboratories to suggest genetic metabolic defects were prepared for trimethylsilylation by treatment with urease...
Vitamin B1 deficiency inhibits the increased conversion of tryptophan to nicotinamide in severe food-restricted rats.Biosci. Biotechnol. Biochem. 79(1) , 103-8, (2015)
The conversion of tryptophan (Trp) → nicotinamide (Nam) is an important pathway for supplying vitamin niacin. We reported the following two phenomena: (1) severe food restriction led to an increase in...
The urinary ratio of 3-hydroxykynurenine/3-hydroxyanthranilic acid is an index to predicting the adverse effects of D-tryptophan in rats.J. Nutr. Sci. Vitaminol. 60(4) , 261-8, (2014)
The adverse effects of D-tryptophan and the possibility of it being a surrogate index for predicting adverse effects in rats were investigated. Male rats were fed one of several test diets (20% casein...
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产品详情:Xanthurenic acid
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产品详情:[Perfemiker]4,8-二羟基喹啉-2-甲酸,96%
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产品详情:黄尿酸
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相关化合物
【黄尿酸】化源网提供黄尿酸CAS号59-00-7,黄尿酸MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询黄尿酸上化源网,专业又轻松。>>电脑版:黄尿酸
标题:黄尿酸_MSDS_用途_密度_黄尿酸CAS号【59-00-7】_化源网 地址:https://www.chemsrc.com/amp/cas/59-00-7_754125.html