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硫酸卡那霉素

硫酸卡那霉素名称

[ CAS 号 ]:
64013-70-3

[ 中文名 ]:
卡那霉素二硫酸盐

[ 英文名 ]:
kanamycin acid sulfate

[中文别名 ]:

[英文别名 ]:

Kanamycin A sulfate
kanamycin A sulphate
Canamycin A disulfate
canamycin monosulfate
kanA sulfate
EINECS 246-933-9
kanamycin A monosulfate

硫酸卡那霉素物理化学性质

[ 熔点 ]:
>260℃

[ 分子式 ]:
C₁₈H₄₀N₄O₁₉S₂

[ 分子量 ]:
680.65600

[ 精确质量 ]:
680.17300

[ PSA ]:
448.57000

[ 外观性状 ]:
white to off-white

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
Soluble in aqueous solutions

硫酸卡那霉素安全信息

[ 符号 ]:

GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H360

[ 警示性声明 ]:
P201-P308 + P313

[ 个人防护装备 ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T

[ 风险声明 (欧洲) ]:
61

[ 安全声明 (欧洲) ]:
53-45

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
29419000

硫酸卡那霉素海关

[ 海关编码 ]: 29419000

硫酸卡那霉素文献

Loss of Slc4a1b chloride/bicarbonate exchanger function protects mechanosensory hair cells from aminoglycoside damage in the zebrafish mutant persephone.

PLoS Genet. 8(10) , e1002971, (2012)

Mechanosensory hair cell death is a leading cause of hearing and balance disorders in the human population. Hair cells are remarkably sensitive to environmental insults such as excessive noise and exp...

Aminoglycosides inhibit KCNQ4 channels in cochlear outer hair cells via depletion of phosphatidylinositol(4,5)bisphosphate.

Mol. Pharmacol. 79 , 51-60, (2011)

Aminoglycoside antibiotics (AGs) are severely ototoxic. AGs cause degeneration of outer hair cells (OHCs), leading to profound and irreversible hearing loss. The underlying mechanisms are not fully un...

Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapes.

Nat. Commun. 6 , 7385, (2015)

Predicting evolutionary paths to antibiotic resistance is key for understanding and controlling drug resistance. When considering a single final resistant genotype, epistatic contingencies among mutat...

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