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二乙胺盐酸盐

二乙胺盐酸盐用途

用于有机合成

二乙胺盐酸盐名称

[ CAS 号 ]:
660-68-4

[ 中文名 ]:
二乙胺盐酸盐

[ 英文名 ]:
Diethylamine hydrochloride

[中文别名 ]:

[英文别名 ]:

N,n-diethylamine hydrochloride
N-Ethylethanamine hydrochloride
N-Ethylethanamine hydrochloride (1:1)
N-Ethylethanaminhydrochlorid
Diethylamine hydrochloride
ethylamine, N-ethyl-, hydrochloride
MFCD00012111
EINECS 200-515-2
Ethanamine, N-ethyl-, hydrochloride (1:1)
Melphalan Impurity 11

二乙胺盐酸盐物理化学性质

[ 密度 ]:
1.0 g/mL at 20 °C

[ 沸点 ]:
320-330 °C

[ 熔点 ]:
227-230 °C(lit.)

[ 分子式 ]:
C₄H₁₂ClN

[ 分子量 ]:
109.598

[ 闪点 ]:
320-330°C

[ 精确质量 ]:
109.065826

[ PSA ]:
12.03000

[ LogP ]:
1.80870

[ 外观性状 ]:
灰白色固体

[ 储存条件 ]:
存放于惰性气体之中;避免湿气 (吸湿)

[ 水溶解性 ]:
soluble

二乙胺盐酸盐MSDS

详细MSDS(安全技术说明书)

二乙胺盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: IA3084000

CHEMICAL NAME :: Diethylamine, hydrochloride

CAS REGISTRY NUMBER :: 660-68-4

LAST UPDATED :: 199701

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C4-H11-N.Cl-H

MOLECULAR WEIGHT :: 109.62

WISWESSER LINE NOTATION :: 2M2 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(1),71,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4860 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 31(1),49,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 960 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 17,475,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1130 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 112,36,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 112,36,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 9500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(1),71,1984 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 546 mg/kg/26W-I

TOXIC EFFECTS :: Liver - liver function tests impaired Kidney, Ureter, Bladder - urine volume increased

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(1),71,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0052 No. of Facilities: 111 (estimated) No. of Industries: 3 No. of Occupations: 19 No. of Employees: 3208 (estimated) No. of Female Employees: 1215 (estimated)

二乙胺盐酸盐安全信息

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S39-S7-S24/25-S36

[ 危险品运输编码 ]:
UN 1993 3/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
SP5740000

[ 海关编码 ]:
29211200

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二乙胺盐酸盐海关

[ 海关编码 ]: 29211200

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Voltage-gated ion channels are transmembrane proteins that undergo complex conformational changes during their gating transitions. Both functional and structural data from K(+) channels suggest that e...

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