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3-Hydroxyterphenyllin

3-Hydroxyterphenyllin用途

3-羟基三苯基林是白曲霉的代谢物。3-羟基三苯基林抑制增殖并对A2780/CP70和OVCAR-3细胞产生细胞毒性。3-羟基三苯基林诱导细胞期阻滞和凋亡。3-羟基三苯基林具有研究卵巢癌的潜力[1][2]。

3-Hydroxyterphenyllin名称

[ CAS 号 ]:
66163-76-6

[ 英文名 ]:
3-Hydroxyterphenyllin

[英文别名 ]:

TERPHENYLLIN,HYDROXY
3-Hydroxyterphenyllin
Hydroxyterphenyllin
AmbotzLS-1090

3-Hydroxyterphenyllin生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 细胞凋亡 >> 细胞凋亡

研究领域 >> 癌症

[参考文献]

[1]. Kurobane I, et al. 3-Hydroxyterphenyllin, a new metabolite of Aspergillus candidus. Structure elucidation by H and C nuclear magnetic resonance spectroscopy. J Antibiot (Tokyo). 1979;32(6):559-564.

[2]. Wang Y, et al. 3-Hydroxyterphenyllin, a natural fungal metabolite, induces apoptosis and S phase arrest in human ovarian carcinoma cells. Int J Oncol. 2017;50(4):1392-1402.

3-Hydroxyterphenyllin物理化学性质

[ 密度 ]:
1.353g/cm3

[ 沸点 ]:
542.8ºC at 760 mmHg

[ 分子式 ]:
C₂₀H₁₈O₆

[ 分子量 ]:
354.35300

[ 闪点 ]:
282.1ºC

[ 精确质量 ]:
354.11000

[ PSA ]:
99.38000

[ LogP ]:
3.86020

[ 折射率 ]:
1.657

3-Hydroxyterphenyllin安全信息

[ 海关编码 ]:
2909499000

3-Hydroxyterphenyllin海关

[ 海关编码 ]: 2909499000

[ 中文概述 ]:
2909499000 其他醚醇及其卤化、磺化、硝化或亚硝化衍生物. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%