1-[(4-chlorophenyl)methyl]-5-fluoropyrimidine-2,4-dione

名称

[ CAS 号 ]:
85093-33-0

[ 英文名 ]:
1-[(4-chlorophenyl)methyl]-5-fluoropyrimidine-2,4-dione

物理化学性质

[ 密度 ]:
1.48g/cm3

[ 分子式 ]:
C₁₁H₈ClFN₂O₂

[ 分子量 ]:
254.64500

[ 精确质量 ]:
254.02600

[ PSA ]:
55.12000

[ LogP ]:
1.78970

[ 折射率 ]:
1.62

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YQ9411500

CHEMICAL NAME :: Uracil, 1-(p-chlorobenzyl)-5-fluoro-

CAS REGISTRY NUMBER :: 85093-33-0

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C11-H8-Cl-F-N2-O2

MOLECULAR WEIGHT :: 254.66

WISWESSER LINE NOTATION :: T6NVMVJ A1R DG& EF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 16,888,1982

安全信息

[ 海关编码 ]:
2933599090

合成路线

详细合成路线

海关

[ 海关编码 ]: 2933599090

[ 中文概述 ]:
2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%