磷酸二乙基伞形酮

磷酸二乙基伞形酮用途

二乙基伞形酮磷酸酯是一种选择性的、有效的胆固醇酯酶抑制剂。它主要通过防止胆固醇转运到类固醇生成细胞的线粒体中来阻止类固醇生成。

磷酸二乙基伞形酮名称

[ CAS 号 ]:
897-83-6

[ 中文名 ]:
磷酸二乙基伞形酮

[ 英文名 ]:
DIETHYLUMBELLIFERYL PHOSPHATE

[英文别名 ]:

Diethylumbelliferyl phosphate
UBP
DEUP

磷酸二乙基伞形酮物理化学性质

[ 密度 ]:
1.272g/cm3

[ 沸点 ]:
408.5ºC at 760 mmHg

[ 分子式 ]:
C₁₃H₁₅O₆P

[ 分子量 ]:
298.22800

[ 闪点 ]:
214.3ºC

[ 精确质量 ]:
298.06100

[ PSA ]:
84.78000

[ LogP ]:
3.35290

[ 外观性状 ]:
无色，黄色粘性液体

[ 折射率 ]:
1.526

[ 储存条件 ]:
20°C

磷酸二乙基伞形酮MSDS

详细MSDS(安全技术说明书)

磷酸二乙基伞形酮安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H300

[ 警示性声明 ]:
P264-P301 + P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T: Toxic;

[ 风险声明 (欧洲) ]:
25

[ 安全声明 (欧洲) ]:
45

[ 危险品运输编码 ]:
UN 2811 6.1/PG 2

[ RTECS号 ]:
GN7350000

磷酸二乙基伞形酮文献

Fungal recognition enhances mannose receptor shedding through dectin-1 engagement.

J. Biol. Chem. 286(10) , 7822-9, (2011)

The mannose receptor (MR) is an endocytic type I membrane molecule with a broad ligand specificity that is involved in both hemostasis and pathogen recognition. Membrane-anchored MR is cleaved by a me...

AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation.

Nat. Commun. 6 , 7176, (2015)

Lipid droplets (LDs) are intracellular organelles that provide fatty acids (FAs) to cellular processes including synthesis of membranes and production of metabolic energy. While known to move bidirect...

Defective triglyceride biosynthesis in CETP-deficient SW872 cells.

J. Lipid Res. 56 , 1669-78, (2015)

We previously reported that reducing the expression of cholesteryl ester transfer protein (CETP) disrupts cholesterol homeostasis in SW872 cells and causes an ∼50% reduction in TG. The causes of this ...

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