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3'-Methyl-4'-methoxyacetophenone

Names

[ CAS No. ]:
10024-90-5

[ Name ]:
3'-Methyl-4'-methoxyacetophenone

[Synonym ]:
3-methyl-4-methoxy-acetophenone
ACETOPHENONE,4'-METHOXY-3'-METHYL
4-methoxy-3-methylacetophenone

Chemical & Physical Properties

[ Density]:
1.018g/cm3

[ Boiling Point ]:
274.3ºC at 760mmHg

[ Molecular Formula ]:
C10H12O2

[ Molecular Weight ]:
164.20100

[ Flash Point ]:
120.3ºC

[ Exact Mass ]:
164.08400

[ PSA ]:
26.30000

[ LogP ]:
2.20620

[ Vapour Pressure ]:
0.00544mmHg at 25°C

[ Index of Refraction ]:
1.504

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AM9275000
CHEMICAL NAME :
Acetophenone, 4'-methoxy-3'-methyl-
CAS REGISTRY NUMBER :
10024-90-5
BEILSTEIN REFERENCE NO. :
2244910
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C10-H12-O2
MOLECULAR WEIGHT :
164.22
WISWESSER LINE NOTATION :
1VR C1 DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1500 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,26,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3600 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,26,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6 mL/kg
TOXIC EFFECTS :
Skin and Appendages - dermatitis, allergic (after systemic exposure)
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,26,1948 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
186 mL/kg/13W-I
TOXIC EFFECTS :
Behavioral - muscle weakness Skin and Appendages - dermatitis, other (after systemic exposure) Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,26,1948

Safety Information

[ HS Code ]:
2914509090

Synthetic Route

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%


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