2-chloroethyl-[2-[(6-chloro-2-methoxyacridin-9-yl)azaniumyl]ethyl]azanium,dichloride
Names
[ CAS No. ]:
10072-24-9
[ Name ]:
2-chloroethyl-[2-[(6-chloro-2-methoxyacridin-9-yl)azaniumyl]ethyl]azanium,dichloride
[Synonym ]:
9-(2-((2-Chloroethyl)amino)ethylamino)-6-chloro-2-methoxyacridine,dihydrochloride
ICR 171
ICR-125
Acridine,9-(2-((2-chloroethyl)amino)ethylamino)-6-chloro-2-methoxy-,dihydrochloride
Quinacrine ethyl M/2
2-chloroethyl-[2-[(6-chloro-2-methoxyacridin-9-yl)azaniumyl]ethyl]azanium dichloride
Chemical & Physical Properties
[ Boiling Point ]:
566.8ºC at 760mmHg
[ Molecular Formula ]:
C18H21Cl4N3O
[ Molecular Weight ]:
437.19100
[ Flash Point ]:
296.6ºC
[ Exact Mass ]:
435.04400
[ PSA ]:
49.41000
[ LogP ]:
5.70710
[ Vapour Pressure ]:
7.23E-13mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AR8050000
- CHEMICAL NAME :
- Acridine, 9-(2-((2-chloroethyl)amino)ethylamino)-6-chloro-2-met hoxy-, dihydrochloride, hydrate
- CAS REGISTRY NUMBER :
- 10072-24-9
- LAST UPDATED :
- 199304
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C18-H19-Cl2-N3-O.2Cl-H.H2-O
- MOLECULAR WEIGHT :
- 454.23
- WISWESSER LINE NOTATION :
- T C666 BNJ EG IM2M2G LO1 &GH 2 &QH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 570 mg/kg/4W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
- REFERENCE :
- JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 36,915,1966