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MJ33 lithium salt

Names

[ CAS No. ]:
1007476-63-2

[ Name ]:
MJ33 lithium salt

[Synonym ]:
MJ33 lithium salt
1-Hexadecyl-3-(trifluoroethyl)-sn-glycero-2-phosphomethanol lithium
Lithium 1-(hexadecyloxy)-3-(2,2,2-trifluoroethoxy)-2-propanyl methyl phosphate
MFCD03787978
Phosphoric acid, 2-(hexadecyloxy)-1-[(2,2,2-trifluoroethoxy)methyl]ethyl methyl ester, lithium salt (1:1)

Biological Activity

[Description]:

MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase
Research Areas >> Metabolic Disease

[References]

[1]. Fisher AB, Dodia C, Chander A, Jain M. A competitive inhibitor of phospholipase A2 decreases surfactant phosphatidylcholine degradation by the rat lung. Biochem J. 1992 Dec 1;288 ( Pt 2)(Pt 2):407-11.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H43F3LiO6P

[ Molecular Weight ]:
498.483

[ Exact Mass ]:
498.290924

Related Compounds