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(R)-5-Hydroxy-1,7-diphenylheptan-3-one

Names

[ CAS No. ]:
100761-20-4

[ Name ]:
(R)-5-Hydroxy-1,7-diphenylheptan-3-one

[Synonym ]:
(5R)-5-Hydroxy-1,7-diphenyl-3-heptanone
3-Heptanone, 5-hydroxy-1,7-diphenyl-, (5R)-

Biological Activity

[Description]:

(R)-5-Hydroxy-1,7-diphenyl-3-heptanone is a diarylheptanoid that can be found in Alpinia officinarum. (R)-5-Hydroxy-1,7-diphenyl-3-heptanone ameliorates oxidative stress and insulin resistance via activation of Nrf2/ARE pathway[1].

[Related Catalog]:

Signaling Pathways >> NF-κB >> Keap1-Nrf2
Research Areas >> Metabolic Disease

[References]

[1]. Zhang X, et, al. DPHC From Alpinia officinarum Ameliorates Oxidative Stress and Insulin Resistance via Activation of Nrf2/ARE Pathway in db/db Mice and High Glucose-Treated HepG2 Cells. Front Pharmacol. 2022 Jan 17;12:792977.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
473.8±33.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H22O2

[ Molecular Weight ]:
282.38

[ Flash Point ]:
201.4±18.0 °C

[ Exact Mass ]:
282.161987

[ LogP ]:
3.55

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.566

[ Storage condition ]:
-20°C

Safety Information

[ Hazard Codes ]:
Xn

Related Compounds