4-(N-[2,4-Diamino-6-pteridinylmethyl]amino)benzoic acid sodium salt

Names

[ CAS No. ]:
100929-45-1

[ Name ]:
4-(N-[2,4-Diamino-6-pteridinylmethyl]amino)benzoic acid sodium salt

[Synonym ]:
sodium,4-[(2,4-diaminopteridin-6-yl)methylamino]benzoate

Chemical & Physical Properties

[ Boiling Point ]:
681.8ºC at 760 mmHg

[ Molecular Formula ]:
C₁₄H₁₂N₇NaO₂

[ Molecular Weight ]:
333.28100

[ Flash Point ]:
366.1ºC

[ Exact Mass ]:
333.09500

[ PSA ]:
155.76000

[ LogP ]:
0.79520

[ Vapour Pressure ]:
1.6E-19mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
20/21/22

[ Safety Phrases ]:
36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Determination of the chiral and achiral related substances of methotrexate by cyclodextrin-modified micellar electrokinetic chromatography.

Electrophoresis 25 , 2830-2837, (2004)

A cyclodextrin-modified micellar electrokinetic chromatographic (CD-MEKC) method for the determination of the most important potential impurities of methotrexate (MTX): 2,4-diamino-6-(hydroxymethyl)pt...