1-Naphthyl phosphate potassium salt

Names

[ Name ]:
1-Naphthyl phosphate potassium salt

[Synonym ]:
naphthalen-1-yl dihydrogen phosphate,potassium

Biological Activity

[Description]:

1-Naphthyl phosphate potassium salt is a non-specific phosphatase inhibitor. 1-Naphthyl phosphate potassium salt decreases the splice-correcting effect[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase

Research Areas >> Others

[In Vitro]

The splice-correcting effect obtained with NickFect1 (NF1) and NickFect2 (NF2) decreases about 50% in the presence of 1-Naphthyl phosphate potassium salt (N7000), whereas PF3 does not respond to the treatment with phosphatase inhibitor. In the presence of 1-Naphthyl phosphate potassium salt the complexes of ON with NF1/2 has less regular shape and lower packing density[1].

[References]

[1]. Nikita Oskolkov, et al. NickFects, Phosphorylated Derivatives of Transportan 10 for Cellular Delivery of Oligonucleotides. International Journal of Peptide Research and Therapeutics volume 17, Article number: 147 (2011).

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₈KO₄P

[ Molecular Weight ]:
262.24000

[ Exact Mass ]:
261.98000

[ PSA ]:
79.40000

[ LogP ]:
2.74950

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport