1H-1,2,4-Triazole-5-propanoicacid, a-amino-

Names

[ Name ]:
1H-1,2,4-Triazole-5-propanoicacid, a-amino-

[Synonym ]:
2-amino-3-(1H-[1,2,4]triazol-3-yl)-propionic acid
2-amino-3-(1H-1,2,4-triazol-5-yl)propanoic acid
EINECS 233-301-2
3-(4h-1,2,4-triazol-3-yl)alanine
1,2,4-Triazole-3-alanine
2-Amino-3-(1H-[1,2,4]triazol-3-yl)-propionsaeure
Triazolealanine
3-(1,2,4-triazol-3-yl)-D,L-alanine

Biological Activity

[Description]:

β-(1,2,4-Triazol-3-yl)-DL-alanine is an alanine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1078.

Chemical & Physical Properties

[ Density]:
1.527g/cm3

[ Boiling Point ]:
454.1ºC at 760mmHg

[ Molecular Formula ]:
C₅H₈N₄O₂

[ Molecular Weight ]:
156.14300

[ Flash Point ]:
228.4ºC

[ Exact Mass ]:
156.06500

[ PSA ]:
104.89000

[ Vapour Pressure ]:
4.9E-09mmHg at 25°C

[ Index of Refraction ]:
1.624

[ Storage condition ]:
−20°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Incorporation of amino acid analogs during the biosynthesis of Escherichia coli aspartate transcarbamylase.

Biochim. Biophys. Acta 615(1) , 59-69, (1980)

Amino acid-requiring mutants capable of producing derepressed levels of aspartate transcarbamylase (carbamoylphosphate:L-aspartate carbamoyltransferase, EC 2.1.3.2) were obtained and used for the inco...

Synthesis of a novel histidine analogue and its efficient incorporation into a protein in vivo.

Protein Eng. 16 , 699-706, (2003)

Proteins containing unnatural amino acids have immense potential in biotechnology and medicine. We prepared several histidine analogues including a novel histidine analogue, beta-(1,2,3-triazol-4-yl)-...

Classifying mutagens as to their specificity in causing the six possible transitions and transversions: a simple analysis using the Salmonella mutagenicity assay.

Environ. Mutagen. 8 , 9, (1986)

The standard Salmonella tester strains used to detect base substitution mutations carry the hisG428 ochre mutation (TA102 and TA104) and the hisG46 missense mutation (TA100). These mutations can be re...