Jaceidin

Names

[ Name ]:
Jaceidin

[Synonym ]:
5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6-dimethoxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6-dimethoxy-
Quercetagetin 3,3',6-trimethyl ether
Jaceidin
3,6,3'-trimethoxy-5,7,4'-trihydroxyflavone
4H-1-Benzopyran-4-one,5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6-dimethoxy
quercetagetin-3,6,3'-trimethylether
5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6-dimethoxy-4H-chromen-4-one
5,7-dihydroxy-2-(4-hydroxy-3-methoxy-phenyl)-3,6-dimethoxy-chromen-4-one
Jaceidine

Biological Activity

[Description]:

Jaceidin is a promising lead molecule for potent VEGFR inhibitor with excellent membrane permeability and oral bioavailability. Jaceidin exhibits anti-tumor activities[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> JAK/STAT Signaling >> EGFR

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR

[References]

[1]. Kazuki Kanazawa, et al. Short photoirradiation induces flavonoid synthesis and increases its production in postharvest vegetables. J Agric Food Chem. 2012 May 2;60(17):4359-68.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
647.8±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₁₆O₈

[ Molecular Weight ]:
360.315

[ Flash Point ]:
238.3±25.0 °C

[ Exact Mass ]:
360.084503

[ PSA ]:
118.59000

[ LogP ]:
1.56

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.680

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2914509090

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%