KCa2 channel modulator 1

Names

[ CAS No. ]:
1019106-73-0

[ Name ]:
KCa2 channel modulator 1

Biological Activity

[Description]:

KCa2 channel modulator 1 (compound 2o) is a potent subtype-selective positive modulator of KCa2 channel. KCa2 channel modulator 1 potentiates human KCa2.3 channels with an EC50 value of 0.19 μM and 0.99 μM on the rat KCa2.2 channel subtype[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[References]

[1]. El-Sayed NS, et al. Structure-Activity Relationship Study of Subtype-Selective Positive Modulators of KCa2 Channels. J Med Chem. 2022;65(1):303-322.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₅ClFN₅

[ Molecular Weight ]:
331.78

KCa2 channel modulator 1

Names

Biological Activity

Chemical & Physical Properties

Related Compounds