ACTH (3-24) (human, bovine, rat)

Names

[ CAS No. ]:
1036763-00-4

[ Name ]:
ACTH (3-24) (human, bovine, rat)

[Synonym ]:
L-Proline, 1-[(2R,8S,11S,14S,17S,20S,23S)-23-[[(2S)-2-amino-3-hydroxy-1-oxopropyl]amino]-11-[3-[(aminoiminomethyl)amino]propyl]-2-(5-aminopentyl)-20-(2-carboxyethyl)-17-(1H-imidazol-4-ylmethyl)-8-(1H-indol-3-ylmethyl)-1,4,7,10,13,16,19,22-octaoxo-14-(phenylmethyl)-26-thia-3,6,9,12,15,18,21-heptaazaheptacos-1-yl]-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-D-lysyl-L-valyl-L-tyrosyl-
1-{(2R)-7-Amino-2-[(L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl)amino]heptanoyl}-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-v alyl-D-lysyl-L-valyl-L-tyrosyl-L-proline

Biological Activity

[Description]:

ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) is the 3-24 fragment of adrenocorticotropic hormone (ACTH). ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) can be used for research of a variety of diseases, including cancer, immune diseases, cardiovascular disease[1].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Cardiovascular Disease
Research Areas >> Inflammation/Immunology
Signaling Pathways >> GPCR/G Protein >> Melanocortin Receptor

[In Vitro]

ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) 可用于预防和/或治疗癌症、自身免疫性疾病、纤维化疾病、炎症疾病、神经退行性疾病、传染病、肺部疾病、心脏和血管疾病以及代谢性疾病[1]。

[References]

[1]. Bevec Dorian, et al. Use of ACTH (3-24) peptide as therapeutic agent: World Intellectual Property Organization, WO2009033787[P]. 2009-03-19.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C125H198N38O27S

[ Molecular Weight ]:
2697.213

[ Exact Mass ]:
2695.500977

[ LogP ]:
-2.73

[ Index of Refraction ]:
1.677

Related Compounds