BM-131246

Names

[ CAS No. ]:
103787-97-9

[ Name ]:
BM-131246

[Synonym ]:
5-[4-[2-(5-methyl-2-phenyloxazol-4-yl)ethoxyl]benzyl]thiazolidine-2,4-dione
5-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzyl}-thiazolidine-2,4-dione
AD-7057
5-(4-(2-(5-methyl-2-phenyloxazol-4-yl)-ethoxy)-benzyl)-thiazolidine-2,4-dione
BM-131246

Biological Activity

[Description]:

BM-131246 is an oral antidiabetic agent.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[In Vivo]

BM-131246 is absorbed quickly and attains approximately proportional increase of the plasma levels in ob/ob mice. After repeated oral doses the terminal half-lives is about 4 h for BM-131246[1].

[References]

[1]. Heitzmann T, et al. Dose proportionality studies of novel thiazolidinedione derivatives as potent antidiabetic agents in mice. Arzneimittelforschung. 1995 Dec;45(12):1284-8.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Molecular Formula ]:
C22H20N2O4S

[ Molecular Weight ]:
408.47000

[ Exact Mass ]:
408.11400

[ PSA ]:
106.73000

[ LogP ]:
4.49440

[ Storage condition ]:
2-8℃

Related Compounds