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Mannioside A

Names

[ CAS No. ]:
1038922-95-0

[ Name ]:
Mannioside A

[Synonym ]:
β-D-Glucopyranoside, (3β,25R)-17-hydroxyspirost-5-en-3-yl 3-O-(6-deoxy-α-L-mannopyranosyl)-
17ALPHA-METHYLTESTOSTERONE
MESTERONE
manioside A
(3β,25R)-17-Hydroxyspirost-5-en-3-yl 3-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
METANDREN
penmesterol
17ALPHA-METHYL-4-ANDROSTEN-17BETA-OL-3-ONE
4-ANDROSTEN-17ALPHA-METHYL-17BETA-OL-3-ONE
Penmestrol

Biological Activity

[Description]:

Mannioside A is a steroidal saponin. Mannioside A is a nature product that could be isolated from Dracaena mannii. Mannioside A has anti-inflammatory effect[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[In Vivo]

Mannioside A (compound 1; 10 mg/kg; p.o.) 抑制 carrageene 诱导的大鼠爪水肿[1]。 Animal Model: Wistar rats[1] Dosage: 10 mg/kg Administration: oral administration Result: Had anti-inflammatory effects with maximum activity observed within 2 h.

[References]

[1]. Tapondjou LA, et, al. In vivo anti-inflammatory effect of a new steroidal saponin, mannioside A, and its derivatives isolated from Dracaena mannii. Arch Pharm Res. 2008 May;31(5):653-8.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
881.7±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C39H62O13

[ Molecular Weight ]:
738.902

[ Flash Point ]:
487.0±34.3 °C

[ Exact Mass ]:
738.419067

[ PSA ]:
196.99000

[ LogP ]:
5.89

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.616

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds