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MMI-0100

Names

[ CAS No. ]:
1039342-24-9

[ Name ]:
MMI-0100

Biological Activity

[Description]:

MMI-0100 is a cell-permeant peptide inhibitor of mitogen activated protein kinase activated protein kinase II (MK2). MMI-0100 reduces intimal hyperplasia ex vivo and in vivo. MMI-0100 suppresses IL-6 expression without effect on IL-8 expression. MMI-0100 suppresses fibrotic processes such as vein graft disease[1].

[Related Catalog]:

Signaling Pathways >> MAPK/ERK Pathway >> MAPKAPK2 (MK2)
Research Areas >> Inflammation/Immunology

[References]

[1]. Akihito Muto, et al. Inhibition of Mitogen Activated Protein Kinase Activated Protein Kinase II with MMI-0100 reduces intimal hyperplasia ex vivo and in vivo. Vascul Pharmacol. Jan-Feb 2012;56(1-2):47-55.

Chemical & Physical Properties

[ Molecular Formula ]:
C98H171N37O26

[ Molecular Weight ]:
2283.64

Related Compounds