4-(4-(bis(2-chloroethyl)amino)phenyl)-1-hydroxybutane-1,1-bisphosphonic acid
Names
[ CAS No. ]:
104233-81-0
[ Name ]:
4-(4-(bis(2-chloroethyl)amino)phenyl)-1-hydroxybutane-1,1-bisphosphonic acid
Chemical & Physical Properties
[ Density]:
1.58g/cm3
[ Boiling Point ]:
762.1ºC at 760mmHg
[ Molecular Formula ]:
C14H23Cl2NO7P2
[ Molecular Weight ]:
450.18800
[ Flash Point ]:
414.7ºC
[ Exact Mass ]:
449.03300
[ PSA ]:
158.15000
[ LogP ]:
2.29480
[ Vapour Pressure ]:
2.05E-24mmHg at 25°C
[ Index of Refraction ]:
1.617
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SZ6800000
- CHEMICAL NAME :
- Phosphonic acid, (4-(4-(bis(2-chloroethyl)amino)phenyl)-1-hydroxybutyl idene)bis-
- CAS REGISTRY NUMBER :
- 104233-81-0
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C14-H23-Cl2-N-O7-P2
- MOLECULAR WEIGHT :
- 450.22
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 146 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 5 mg/plate
- REFERENCE :
- JCROD7 Journal of Cancer Research and Clinical Oncology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.93- 1979- Volume(issue)/page/year: 111,209,1986