<Suppliers Price>

α-MSH free acid

Names

[ CAS No. ]:
10466-28-1

[ Name ]:
α-MSH free acid

[Synonym ]:
ACETYL-ACTH (1-13)
AC-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL: AC-SYSMEHFRWGKPV
a-MSH

Biological Activity

[Description]:

α-MSH (free acid) is a MC3R and MC4R agonist with a EC50 of 0.16±0.09 nM and 5.6±6.8 nM,respectively. α-MSH (free acid) activates cAMP generation at MC3R and MC4R[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> GPCR/G Protein >> Melanocortin Receptor

[References]

[1]. [1] Miwa H, et al. Structural determinants of the melanocortin peptides required for activation of melanocortin-3 and melanocortin-4 receptors. J Pharmacol Exp Ther. 1995;273(1):367-372.

Chemical & Physical Properties

[ Density]:
1.48±0.1 g/cm3

[ Molecular Formula ]:
C77H108N20O20S

[ Molecular Weight ]:
1665.87

[ Exact Mass ]:
1664.78000

[ PSA ]:
662.49000

[ LogP ]:
2.58240

[ Storage condition ]:
20°C

Safety Information

[ WGK Germany ]:
3


Related Compounds