MCC

Names

[ CAS No. ]:
104676-09-7

[ Name ]:
MCC

Biological Activity

[Description]:

MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[In Vitro]

Antibody-drug conjugates (ADCs) are potent cytotoxic drugs linked to antibodies through chemical linkers, and allow specific targeting of drugs to neoplastic cells. Anti-CD22-MCC-DM1 is broadly effective in vitro against multiple NHL cell lines[1].

[References]

[1]. Polson AG, et al. Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma. Leukemia. 2010;24(9):1566-1573.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₁₆N₂O₃

[ Molecular Weight ]:
236.27

[ Storage condition ]:
2-8°C

MCC

Names

Biological Activity

Chemical & Physical Properties

Related Compounds