Ganoderic acid K

Names

[ Name ]:
Ganoderic acid K

[Synonym ]:
6-((3S,5R,7S,10S,12S,13R,14R)-12-Acetoxy-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-4-oxo-heptanoic acid

Biological Activity

[Description]:

Ganoderic acid K is a potent angiotensin converting enzyme inhibitor. Ganoderic acid K is a triterpene that can be found in ganoderma lucidum[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)

[References]

[1]. Morigiwa A, et al. Angiotensin converting enzyme-inhibitory triterpenes from Ganoderma lucidum. Chem Pharm Bull (Tokyo). 1986 Jul;34(7):3025-8.

Chemical & Physical Properties

[ Density]:
1.25±0.1 g/cm3

[ Boiling Point ]:
723.7±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₂H₄₆O₉

[ Molecular Weight ]:
574.70200

[ Exact Mass ]:
574.31400

[ PSA ]:
155.27000

[ LogP ]:
3.67310

Ganoderic acid K

Names

Biological Activity

Chemical & Physical Properties

Related Compounds