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Ganoderol A

Names

[ CAS No. ]:
104700-97-2

[ Name ]:
Ganoderol A

[Synonym ]:
ganoderol A
(24E)-26-Hydroxylanosta-7,9(11),24-trien-3-one
Ganodermenonol
Lanosta-7,9(11),24-trien-3-one, 26-hydroxy-, (24E)-

Biological Activity

[Description]:

Ganoderol A is a terpenoid extracted from Ganoderma lucidum with antimicrobial activities. Ganoderol A inhibits cholesterol synthesis pathway and has significant anti-inflammatory activity and protection against ultraviolet A (UVA) damage[1][2].

[Related Catalog]:

Research Areas >> Infection
Research Areas >> Inflammation/Immunology
Research Areas >> Metabolic Disease
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Hassan Hajjaj, et al. Effect of 26-oxygenosterols From Ganoderma Lucidum and Their Activity as Cholesterol Synthesis Inhibitors. Appl Environ Microbiol. 2005 Jul;71(7):3653-8.

[2]. Fujun Jin, et al. In vitro Protective Effect of Ganoderol A Isolated from Ganadermalucidum Against Ultraviolet A Radiation and its Anti-inflammatory Properties. Trop. J. Pharm. Res., 2015, 14(3):412-21.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
550.9±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C30H46O2

[ Molecular Weight ]:
438.685

[ Flash Point ]:
231.8±22.7 °C

[ Exact Mass ]:
438.349792

[ PSA ]:
37.30000

[ LogP ]:
8.53

[ Vapour Pressure ]:
0.0±3.4 mmHg at 25°C

[ Index of Refraction ]:
1.546

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds