N,N'-Diethylthiourea
Names
[ CAS No. ]:
105-55-5
[ Name ]:
N,N'-Diethylthiourea
[Synonym ]:
1,3-diethylthiourea
MFCD00004925
1,3-Diethyl-2-thiourea
EINECS 203-308-5
N,N‘-Diethylthiourea
DETU
Chemical & Physical Properties
[ Density]:
1,12 g/cm3
[ Boiling Point ]:
169.2ºC at 760 mmHg
[ Melting Point ]:
76-78 °C(lit.)
[ Molecular Formula ]:
C5H12N2S
[ Molecular Weight ]:
132.22700
[ Flash Point ]:
186 °C
[ Exact Mass ]:
132.07200
[ PSA ]:
56.15000
[ LogP ]:
1.27210
[ Vapour Pressure ]:
1.56mmHg at 25°C
[ Index of Refraction ]:
1.505
[ Stability ]:
Stable. May be air sensitive. Incompatible with strong oxidizing agents.
[ Water Solubility ]:
38 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YS9800000
- CHEMICAL NAME :
- Urea, 1,3-diethyl-2-thio-
- CAS REGISTRY NUMBER :
- 105-55-5
- BEILSTEIN REFERENCE NO. :
- 0773905
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 15
- MOLECULAR FORMULA :
- C5-H12-N2-S
- MOLECULAR WEIGHT :
- 132.25
- WISWESSER LINE NOTATION :
- SUYM1&M1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 316 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 62 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 11 gm/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Endocrine - thyroid tumors
MUTATION DATA
- TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - hamster Embryo
- DOSE/DURATION :
- 550 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 356,85,1996 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84809 No. of Facilities: 487 (estimated) No. of Industries: 6 No. of Occupations: 8 No. of Employees: 11186 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84809 No. of Facilities: 1141 (estimated) No. of Industries: 24 No. of Occupations: 28 No. of Employees: 11484 (estimated) No. of Female Employees: 739 (estimated)
Safety Information
[ Symbol ]:
GHS05, GHS07, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302 + H312-H317-H318-H372-H412
[ Precautionary Statements ]:
P260-P280-P301 + P312 + P330-P305 + P351 + P338 + P310
[ Target Organs ]:
Thyroid.
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R40
[ Safety Phrases ]:
S45-S36/37
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
YS9800000
[ HS Code ]:
29309070
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2930909090
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%