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m-PEG5-succinimidyl carbonate

Names

[ CAS No. ]:
1058691-00-1

[ Name ]:
m-PEG5-succinimidyl carbonate

[Synonym ]:
MFCD30828680

Biological Activity

[Description]:

m-PEG5-succinimidyl carbonate is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Research Areas >> Inflammation/Immunology

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Riggs-Sauthier, Jennifer, et al. Water-soluble oligomer-containing derivatives as protease inhibitor conjugates and their preparation and pharmaceutical compositions. Patent WO2008112289A2.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H27NO10

[ Molecular Weight ]:
393.39

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds