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m-PEG6-CH2CH2CHO

Names

[ CAS No. ]:
1058691-77-2

[ Name ]:
m-PEG6-CH2CH2CHO

[Synonym ]:
MPEG7-ALD

Biological Activity

[Description]:

m-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Erwin R. Boghaert, et al. Anti-egfr antibody drug conjugates. WO2017214282A1.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
424.7±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H32O8

[ Molecular Weight ]:
352.421

[ Flash Point ]:
182.2±27.4 °C

[ Exact Mass ]:
352.209717

[ LogP ]:
-2.30

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.442

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds