N6-Methyl-dA phosphoramidite

Names

[ Name ]:
N6-Methyl-dA phosphoramidite

[Synonym ]:
Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[[bis(1-methylethyl)amino](2-cyanoethyl)phosphino]-2'-deoxy-N-methyl-
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethyl)(diisopropylamino)phosphino]-2'-deoxy-N-methyladenosine
N6-METHYL-DA CEP
2'-Deoxy-5'-O-DMT-N6-methyladenosine 3'-CE phosphoramidite

Biological Activity

[Description]:

N6-Methyl-dA phosphoramidite can be used in the synthesis of oligodeoxyribonucleotides[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Li D, et, al. Exocyclic carbons adjacent to the N6 of adenine are targets for oxidation by the Escherichia coli adaptive response protein AlkB. J Am Chem Soc. 2012 May 30;134(21):8896-901.

Chemical & Physical Properties

[ Boiling Point ]:
862.0±75.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄₁H₅₀N₇O₅P

[ Molecular Weight ]:
751.853

[ Flash Point ]:
475.1±37.1 °C

[ Exact Mass ]:
751.361084

[ PSA ]:
142.40000

[ LogP ]:
8.48

[ Vapour Pressure ]:
0.0±3.3 mmHg at 25°C

[ Storage condition ]:
2-8℃

N6-Methyl-dA phosphoramidite

Names

Biological Activity

Chemical & Physical Properties

Related Compounds