BW A4C

Names

[ Name ]:
BW A4C

[Synonym ]:
Acetamide,N-hydroxy-N-(3-(3-phenoxyphenyl)-2-propenyl)
(E)-N-hydroxy-N-(3-(3-phenoxyphenyl)allyl)acetamide
BW4C
N-[(E)-3-(3-Phenoxyphenyl)prop-2-enyl]acetohydroxamic acid
N-(3-phenoxycinnamyl)-acetohydroxamic acid
BWA4C

Chemical & Physical Properties

[ Density]:
1.201g/cm3

[ Boiling Point ]:
464.9ºC at 760 mmHg

[ Melting Point ]:
79.3-80.1ºC(lit.)

[ Molecular Formula ]:
C₁₇H₁₇NO₃

[ Molecular Weight ]:
283.32200

[ Flash Point ]:
235ºC

[ Exact Mass ]:
283.12100

[ PSA ]:
49.77000

[ LogP ]:
3.72980

[ Vapour Pressure ]:
1.92E-09mmHg at 25°C

[ Index of Refraction ]:
1.622

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Effect of polyunsaturated fatty acids on the growth of murine colon adenocarcinomas in vitro and in vivo.

Br. J. Cancer 70(1) , 6-10, (1994)

The effect of the polyunsaturated fatty acids (PUFAs) linoleic acid (LA) and arachidonic acid (AA) on the growth of two murine colon adenocarcinoma cell lines (MAC26 and MAC13) has been determined bot...

The 5-lipoxygenase inhibitor BWA4C impairs osteoclastic resorption in a synchronized model of bone remodeling.

Bone 17(2) , 185-91, (1995)

The role of leukotrienes on bone resorption was tested in a well-standardized model of bone remodeling by inhibiting their biosynthesis with BWA4C, a specific inhibitor of 5-lipoxygenase. After extrac...

A test system for leukotriene synthesis inhibitors based on the in-vitro differentiation of the human leukemic cell lines HL-60 and Mono Mac 6.

Naunyn Schmiedebergs Arch. Pharmacol. 356(4) , 441-5, (1997)

Differentiation of HL-60 cells along the granulocytic lineage by DMSO in the presence of transforming growth factor-beta and low concentrations of 1,25-dihydroxyvitamin D3 leads to the upregulation of...