2-Phenylethanol-d4

Names

[ CAS No. ]:
107473-33-6

[ Name ]:
2-Phenylethanol-d4

[Synonym ]:
1,1,2,2-tetradeuterio-2-phenyl-ethanol
2-phenylethyl mercaptan
1,2-phenylethylmercaptane
Benzeneethanethiol
2-phenylethanol-1,1,2,2-d4
Phenethyl mercaptan
2-phenyl-ethanethiol
Phenylethyl mercaptan
2-mercaptophenylethane
1.1.2.2-Tetradeutero-2-phenylethylalkohol
2-phenyl-1-ethanethiol

Biological Activity

[Description]:

2-Phenylethanol-d4 is the deuterium labeled 2-Phenylethanol[1]. 2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans[2]. It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Lingappa BT, et al. Phenethyl alcohol and tryptophol: autoantibiotics produced by the fungus Candida albicans. Science. 1969 Jan 10;163(3863):192-4.  

Chemical & Physical Properties

[ Molecular Formula ]:
C8H6D4O

[ Molecular Weight ]:
126.18900

[ Exact Mass ]:
126.09800

[ PSA ]:
20.23000

[ LogP ]:
1.22140

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds