1-[2-(4-Bromophenoxy)ethyl]pyrrolidine

Names

[ Name ]:
1-[2-(4-Bromophenoxy)ethyl]pyrrolidine

[Synonym ]:
1-[2-(4-Bromophenoxy)ethyl]pyrrolidine
Pyrrolidine, 1-[2-(4-bromophenoxy)ethyl]-
EINECS 214-100-9
MFCD03093182
Pyrrolidine, 1-[2-(p-bromophenoxy)ethyl]-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
331.5±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₆BrNO

[ Molecular Weight ]:
270.165

[ Flash Point ]:
163.3±22.3 °C

[ Exact Mass ]:
269.041504

[ PSA ]:
12.47000

[ LogP ]:
3.61

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.560

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

First generation 5-vinyl-3-pyridinecarbonitrile PKCtheta inhibitors.

Bioorg. Med. Chem. Lett. 19 , 5829, (2009)

A series of 5-vinyl-3-pyridinecarbonitriles were synthesized and evaluated as PKCtheta inhibitors. The systematic optimization of 4-[(4-methyl-1H-indol-5-yl)amino]-5-[(E)-2-phenylvinyl]-3-pyridinecarb...