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Icariside B1

Names

[ CAS No. ]:
109062-00-2

[ Name ]:
Icariside B1

[Synonym ]:
(1S,3R,4R)-3-Hydroxy-3,5,5-trimethyl-4-(3-oxo-1-buten-1-ylidene)cyclohexyl β-D-glucopyranoside
3-Buten-2-one, 4-[(1R,2R,4S)-4-(β-D-glucopyranosyloxy)-2-hydroxy-2,6,6-trimethylcyclohexylidene]-, (3R)-
(1S,3R,4R)-3-hydroxy-3,5,5-trimethyl-4-(3-oxobut-1-en-1-ylidene)cyclohexyl β-D-glucopyranoside

Biological Activity

[Description]:

Icariside B1 is a megastigmane glycoside compound isolated from Petasites tricholobus Franch, with an anticancer effect[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Yong Zhang, et al. Two new sulfated sesquiterpenoids from Petasites tricholobus. Yao Xue Xue Bao. 2014 Oct;49(10):1433-7.

[2]. Nguyen Thi Thu Hien, et al. Chemical constituents of the Annona glabra fruit and their cytotoxic activity. Pharm Biol. 2015;53(11):1602-7.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
602.7±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H30O8

[ Molecular Weight ]:
386.437

[ Flash Point ]:
210.4±25.0 °C

[ Exact Mass ]:
386.194061

[ LogP ]:
-1.41

[ Vapour Pressure ]:
0.0±3.9 mmHg at 25°C

[ Index of Refraction ]:
1.566

[ Storage condition ]:
2-8℃

Related Compounds