H-Tyr-Ile-Gly-Ser-Arg-OH trifluoroacetate salt

Names

[ Name ]:
H-Tyr-Ile-Gly-Ser-Arg-OH trifluoroacetate salt

[Synonym ]:
tyrosyl-isoleucyl-glycyl-seryl-arginine
Laminin Fragment 929-933
LAMININ FRAGMENT 929-933
LAMININ B1 CHAIN PENTAPEPTIDE FRAGMENT
Laminin (929-933)
LAMININ FRAGMENT
LAMININ PENTAPEPTIDE
YIGSR
Tyrosinyl-isoleucinyl-glycinyl-serinyl-arginine

Biological Activity

[Description]:

YIGSR is a peptide that can inhibit the tumour growth and metastasis of leukaemic cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. N Yoshida, et al. The laminin-derived peptide YIGSR (Tyr–Ile–Gly–Ser–Arg) inhibits human pre-B leukaemic cell growth and dissemination to organs in SCID mice. Br J Cancer. 1999 Aug; 80(12): 1898–1904.

Chemical & Physical Properties

[ Density]:
1.44 g/cm3

[ Molecular Formula ]:
C₂₆H₄₂N₈O₈

[ Molecular Weight ]:
594.66000

[ Exact Mass ]:
594.31300

[ PSA ]:
282.08000

[ LogP ]:
0.67370

[ Index of Refraction ]:
1.633

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Multifactorial optimization of endothelial cell growth using modular synthetic extracellular matrices.

Integr. Biol. (Camb.) 3(3) , 185-96, (2011)

Extracellular matrices (ECMs) are complex materials, containing at least dozens of different macromolecules that are assembled together, thus complicating their optimization towards applications in 3D...

Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor.

FASEB J. 20(7) , 906-15, (2006)

It has been reported that extracellular matrix (ECM) molecules regulate monocyte activation by binding with a 67 kDa nonintegrin laminin receptor (LR). As microgliosis is a pivotal factor in propellin...

Malignancy-related 67kDa laminin receptor in adenoid cystic carcinoma. Effect on migration and beta-catenin expression.

Oral Oncol. 43(10) , 987-98, (2007)

Adenoid cystic carcinoma is a malignant salivary gland neoplasm with recurrence and metastasis. We studied the expression of a malignancy-related non-integrin laminin receptor, the 67LR, in this neopl...