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5'-O-DMT-N4-Bz-2'-OMe-rC

Names

[ CAS No. ]:
110764-74-4

[ Name ]:
5'-O-DMT-N4-Bz-2'-OMe-rC

[Synonym ]:
N4-benzoyl-5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-methylcytidine
HG1340
5'-O-dimethoxytrityl-4N-benzoyl-2'-O-methylcytidine
5'-O-DMT-N4-BENZOYL-2'-O-METHYL-CYTIDINE
8362P
5'-O-DMT-N4-Bz-2'-OMe-rC

Biological Activity

[Description]:

DMT-2'-OMe-Bz-C is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.  

Chemical & Physical Properties

[ Density]:
1.27±0.1 g/cm3(Predicted)

[ Molecular Formula ]:
C38H37N3O8

[ Molecular Weight ]:
663.72

[ Exact Mass ]:
663.25800

[ PSA ]:
133.86000

[ LogP ]:
4.62900

Related Compounds