(E)-Thiacloprid

Names

[ CAS No. ]:
111988-49-9

[ Name ]:
(E)-Thiacloprid

[Synonym ]:
(3-((6-chloro-3-pyridinyl)methyl)-2-thiazolidinylidene)cyanamide
Cyanamide, N-[(2E)-3-[(6-chloro-3-pyridinyl)methyl]-2-thiazolidinylidene]-
{(2E)-3-[(6-Chloro-3-pyridinyl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide
Cyanamide, (3-((6-chloro-3-pyridinyl)methyl)-2-thiazolidinylidene)-
(Z)-3-(6-chloro-3-pyridylmethyl)-1,3-thiazolidin-2-ylidenecyanamide
{(2Z)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide
[3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene]cyanamide
(Z)-[3-[(6-chloro-3-pyridinyl)methyl]-2-thiazolidinylidene]cyanamide
{(2E)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide
Thiacloprid
MFCD02101042

Biological Activity

[Description]:

Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables[1]. Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions[2].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Schuld, M., et al. Effects of Thiacloprid, a New Chloronicotinyl Insecticide, On the Egg Parasitoid Trichogramma cacaoeciae. Ecotoxicology 9, 197–205 (2000).

[2]. Verebová V, Želonková K, Holečková B, Staničová J. The effect of neonicotinoid insecticide thiacloprid on the structure and stability of DNA. Physiol Res. 2019;68(Suppl 4):S459-S466.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
423.1±55.0 °C at 760 mmHg

[ Melting Point ]:
136ºC

[ Molecular Formula ]:
C₁₀H₉ClN₄S

[ Molecular Weight ]:
252.723

[ Flash Point ]:
209.7±31.5 °C

[ Exact Mass ]:
252.023651

[ PSA ]:
77.58000

[ LogP ]:
0.55

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.691

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H332-H336-H351-H360FD-H410

[ Precautionary Statements ]:
Missing Phrase - N15.00950417-P201-P261-P280-P308 + P313

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/22

[ Safety Phrases ]:
S60

[ RIDADR ]:
2588

[ RTECS ]:
GS6093749

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Articles

Capillary electrophoresis-mass spectrometry as a new approach to analyze neonicotinoid insecticides.

J. Chromatogr. A. 1359 , 317-24, (2014)

This paper represents the first report of a capillary electrophoresis (CE) method compatible with mass spectrometry (MS) detection for simultaneously analyzing seven neonicotinoid insecticides (acetam...

Simultaneous determination of neonicotinoid insecticides in human serum and urine using diatomaceous earth-assisted extraction and liquid chromatography-tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 969 , 85-94, (2014)

A rapid and sensitive analytical method was developed for simultaneous determination of eight neonicotinoid insecticides (acetamiprid, clothianidin, dinotefuran, flonicamid, imidacloprid, nitenpyram, ...

Simultaneous determination of neonicotinoid insecticides in sunflower-treated seeds (hull and kernel) by LC-MS/MS.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 33 , 442-51, (2016)

A validated analytical method to determine seven neonicotinoids (dinotefuran, nitenpyram, thiamethoxam, clothianidin, imidacloprid, acetamiprid and thiacloprid) in sunflower seeds (hull and kernel) us...