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Triethylene Glycol Monoethyl Ether

Names

[ CAS No. ]:
112-50-5

[ Name ]:
Triethylene Glycol Monoethyl Ether

[Synonym ]:
Triethylene Glycol Monoethyl Ether
UNII-4G0E2G9582
Ethyltriglycol
3,6,9-Trioxaundecan-1-ol
Ethanol, 2-(2-(2-ethoxyethoxy)ethoxy)-
2-(2-(2-Ethoxyethoxy)ethoxy)ethanol
MFCD00020605
EINECS 203-978-9
Ethanol, 2-[2-(2-ethoxyethoxy)ethoxy]-
Ethoxytriglycol
Tri(ethylene glycol) monoethyl ether
triethylene glycol ethyl ether
2-[2-(2-ethoxyethoxy)ethoxy]ethanol

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
256.0±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C8H18O4

[ Molecular Weight ]:
178.226

[ Flash Point ]:
106.4±21.8 °C

[ Exact Mass ]:
178.120514

[ PSA ]:
47.92000

[ LogP ]:
-0.98

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.431

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KK8950000
CHEMICAL NAME :
Ethanol, 2-(2-(2-ethoxyethoxy)ethoxy)-
CAS REGISTRY NUMBER :
112-50-5
BEILSTEIN REFERENCE NO. :
1700466
LAST UPDATED :
199710
DATA ITEMS CITED :
13
MOLECULAR FORMULA :
C8-H18-O4
MOLECULAR WEIGHT :
178.26
WISWESSER LINE NOTATION :
Q2O2O2O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 47(5),84,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5799 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 47(5),84,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
8 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
3070 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 47(5),84,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
141 mg/kg/26W-I
TOXIC EFFECTS :
Blood - changes in leukocyte (WBC) count Blood - changes in platelet count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 47(5),84,1982 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2556 No. of Facilities: 12848 (estimated) No. of Industries: 83 No. of Occupations: 25 No. of Employees: 81218 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2556 No. of Facilities: 70 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 621 (estimated) No. of Female Employees: 44 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US);type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
-

[ RTECS ]:
KK8950000

[ HS Code ]:
2909499000

Synthetic Route

Customs

[ HS Code ]: 2909499000

[ Summary ]:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

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