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Garcinone E

Names

[ CAS No. ]:
112649-21-5

[ Name ]:
Garcinone E

[Synonym ]:
garcinone-E
2,3,6,8-Tetrahydroxy-1,4,7-tris-(3-methyl-but-2-enyl)-xanthen-9-one

Biological Activity

[Description]:

Garcinone E is a natural xanthone found in the rind of the mangosteen fruit. Garcinone E induces apoptosis and inhibits cancer cell migration. Garcinone E has anticancer effects on different human cancer cell lines, including colorectal, breast, and hepatocellular carcinomas[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[References]

[1]. Linli Yang, et al. Garcinone-E exhibits anticancer effects in HeLa human cervical carcinoma cells mediated via programmed cell death, cell cycle arrest and suppression of cell migration and invasion. AMB Express. 2020 Jul 16;10(1):126.  

Chemical & Physical Properties

[ Density]:
1.240±0.06 g/cm3(Predicted)

[ Boiling Point ]:
694.9±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C28H32O6

[ Molecular Weight ]:
464.55000

[ Exact Mass ]:
464.22000

[ PSA ]:
111.13000

[ LogP ]:
6.29470

Related Compounds