Glycine-1-13C,15N

Names

[ Name ]:
Glycine-1-13C,15N

[Synonym ]:
13C and 15N Labeled aminoacetic acid,13C and 15N Labeled glycine
Acetic acid, amino-
グリシン
Glycocoll
H2N-CH2-COOH
Glycine
2-Aminoacetic acid
Aminoacetic acid
UNII-TE7660XO1C
glycine zwitterion
Aminoethanoic acid
Gly
MFCD00064425
Z1VQ
amino-Acetic acid

Biological Activity

[Description]:

Glycine-1-13C,15N is the 13C- and 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR

Research Areas >> Neurological Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
240.9±23.0 °C at 760 mmHg

[ Melting Point ]:
240ºC (dec.)(lit.)

[ Molecular Formula ]:
C₁₃CH₅₁₅NO₂

[ Molecular Weight ]:
75.067

[ Flash Point ]:
99.5±22.6 °C

[ Exact Mass ]:
75.032028

[ PSA ]:
63.32000

[ LogP ]:
-1.03

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.461

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3